Description
Environmental Risk Assessment: A Toxicological Approach by Ted Simon EBOOK PDF Instant Download
Table of Content
Introduction
Risk Assessment Paradigm from the 1983 Redbook-“Risk Assessment in the Federal Government: Managing the Process”
Risk Assessment Guidance for Superfund (RAGS) Part A 1989
The Interface of Risk Assessment and Risk Management
History of Risk Assessment in the US from 1990 to 2010
Risk Communication and Stakeholder Participation
Risk Assessment Policy and the Role of Science
How Risk is Perceived and Expressed
Actuarial Risk
Predicted Risk
Perceived Risk
Risk Estimates for Regulation
Uncertainty in Risk Estimates
Uncertainty in Risk Management and the Precautionary Principle
Human Health Exposure Assessment
What are Receptors?
How are Receptors Exposed to Environmental Stressors?
Human Exposure Assessment
Assessing Exposure Factors and Data
Issues to Be Considered When Performing an Exposure Assessment
The Concentration Term
Fate and Transport Models
Accounting For Uncertainty In Exposure Factors
Toxicity Assessment for Human Health Risk Assessment
Mode of Action and General Aspects of Toxicity
Homeostasis and Thresholds
Historical Perspective on Toxicity Testing
Timescale and Nature of Adverse Effects
Dose-Response Assessment
Low Dose Extrapolation-Two Types of Toxicity Factors
Computational Methods in Toxicity Assessment
Mixtures
Accounting For Uncertainty in Toxicity Factors
Toxicity Factors for Regulation
Risk Characterization
Hazard Quotient for Threshold Effects
Risk Estimation for Non-Threshold Effects
Cumulative and Aggregate Risk
The Possibility of Compounding Conservatism in Both Exposure and Toxicity
The Precautionary Principle
Utility of Risk Characterization for Decision Making
Ecological Risk Assessment
Statutory Aspects of ERA at EPA and the Role of Natural Resource Trustees
ERA Under REACH
Ecological Risk Assessment as Practiced By EPA
Methodology for ERA under REACH
Science Policy of ERA
The Future of Risk Assessment
In Vitro Testing and ‘Omics-Toxicity Testing in the 21st Century
Science and Decisions: Advancing Risk Assessment
Recommendations for Improving IRIS in the 2011 NAS Review of the Formaldehyde Risk Assessment
Possible Future Scenarios for Risk Assessment: Scientific, Social and Political Factors in Societal Decision Making
Appendix A: Useful Methods and Algorithms for Probabilistic Risk Assessment (PRA)
